The Best Gluten-Free Meatloaf Ever

  • Servings: 6-8
  • Difficulty: Easy

This isn’t just another meatloaf recipe! I have made many meatloaf variations throughout the years, but none have ever come close to this super easy, flavorful, moist, and absolutely delicious meatloaf that my daughter Tracy makes. I’ve been staying with my daughter while she is recovering from surgery and wanted to cook meals for her and, as she refers to him, her roommate John🤣. The only change I had to make was adapting it to be gluten-free for Jack so he could enjoy it too. I have to say it was the biggest hit. The glaze was just the right amount of sweet and tangy that made this meatloaf extra special. Enjoy !!😋 😋


  • 1½-1¾ lbs ground beef 80-85%
  • 1¾ cups 4C Gluten-Free Plain breadcrumbs
  • 1 yellow onion, diced
  • 1 cup whole milk
  • 2 large eggs, beaten
  • 4 Tablespoons ketchup
  • 2 Tablespoons Worcestershire sauce
  • 2-3 tsp dried parsley
  • 3 tsp garlic powder
  • Salt to taste

Gluten-Free Homemade Onion Soup Mix

  • 1/2 cup dried onion flakes
  • 4 Tablespoons Gluten-free beef bouillon granules (Herb-ox)
  • 1/2 tsp onion powder
  • 1/2 tsp dried parsley flakes
  • 1/4 tsp celery seed
  • 1/4 tsp paprika
  • 1/4 tsp freshly ground black pepper

Glaze Topping

  • 1/2 cup ketchup
  • 2 Tablespoons red wine vinegar
  • 4 heaping Tablespoons brown sugar


  • Preheat oven to 350º F.
  • In a large bowl, add the ground beef, bread crumbs, onion, milk, beaten eggs,  4 tablespoons ketchup, Worcestershire sauce, parsley, salt, garlic powder, dried onion flakes, celery seed, paprika, bouillon granules, and pepper. Using disposable gloves on your hands mix these ingredients together until well combined. Do not under-mix.
  • Add the meat mixture to a 9×13 inch roasting pan. Pat and form the meat into a loaf shape approximately 3-4 inches high.
  • In a small bowl, add 1/2 cup ketchup, the brown sugar, and vinegar. Stir well to combine. Pour the glaze on top of the meatloaf and place it on the center rack in the preheated oven.
  • Bake uncovered for 55 -65 minutes.
  • Let the meatloaf rest for 8-10 minutes before serving.


1. Homemade Gluten-free onion soup mix. Mix all ingredients together. Store in an airtight container. This will yield the equivalent of 2 envelopes of gluten-free dry onion soup mix.

2. If gluten isn’t an issue you may use any Lipton Onion Soup mix in place of the homemade version and regular plain breadcrumbs.

2. For a tasty meal, serve with creamy mashed potatoes and sautéed fresh spinach with garlic and EVOO

Did you make this recipe? We would love to hear from you. Please leave us a comment below or Tag @twiinsinthekitchen on Instagram and hashtag it #twiinsinthekitchen.

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